| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKL35107.1 | ppk1 | AB185_14910 | AB185_14905 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.508 |
| AKL35107.1 | ppx | AB185_14910 | AB185_14900 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GppA/Ppx family. | 0.508 |
| gppA | phoR | AB185_06245 | AB185_29815 | Guanosine polyphosphate pyrophosphohydrolase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.421 |
| gppA | ppk1 | AB185_06245 | AB185_14905 | Guanosine polyphosphate pyrophosphohydrolase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.779 |
| gppA | ppx | AB185_06245 | AB185_14900 | Guanosine polyphosphate pyrophosphohydrolase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GppA/Ppx family. | 0.911 |
| gppA | pstB | AB185_06245 | AB185_07170 | Guanosine polyphosphate pyrophosphohydrolase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.432 |
| phoR | gppA | AB185_29815 | AB185_06245 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanosine polyphosphate pyrophosphohydrolase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. | 0.421 |
| phoR | phoU | AB185_29815 | AB185_07175 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.851 |
| phoR | pitA | AB185_29815 | AB185_08680 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.728 |
| phoR | ppa_1 | AB185_29815 | AB185_22320 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Potassium ABC transporter ATPase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.501 |
| phoR | ppa_2 | AB185_29815 | AB185_33470 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.545 |
| phoR | ppk1 | AB185_29815 | AB185_14905 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.531 |
| phoR | ppx | AB185_29815 | AB185_14900 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GppA/Ppx family. | 0.582 |
| phoR | pstB | AB185_29815 | AB185_07170 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.736 |
| phoU | phoR | AB185_07175 | AB185_29815 | Transcriptional regulator PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.851 |
| phoU | pitA | AB185_07175 | AB185_08680 | Transcriptional regulator PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.633 |
| phoU | ppk1 | AB185_07175 | AB185_14905 | Transcriptional regulator PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.546 |
| phoU | ppx | AB185_07175 | AB185_14900 | Transcriptional regulator PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GppA/Ppx family. | 0.452 |
| phoU | pstB | AB185_07175 | AB185_07170 | Transcriptional regulator PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.996 |
| pitA | phoR | AB185_08680 | AB185_29815 | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.728 |