STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yffBReductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (117 aa)    
Predicted Functional Partners:
dapE_1
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
  
    0.833
AKL35130.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.741
arsC-2
Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.683
arsC
Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.680
nifH
Nitrogenase reductase; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
     
 0.651
isfD
Sulfoacetaldehyde reductase; Catalyzes the formation of isethionate from 2- sulfoacetaldehyde in the deaminative pathway of taurine. The enzyme is specific for NADPH; NADH is not a substrate. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.600
hslO
Hsp33-like chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
 
   
 0.572
nifD
Nitrogenase molybdenum-iron protein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.560
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.518
AKL33428.1
Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.512
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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