Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yffBReductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (117 aa)    
Predicted Functional Partners:
dapE_1
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
  
    0.864
AKL35130.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.741
arsC
Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.667
nifH
Nitrogenase reductase; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
     
 0.633
arsC-2
Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.604
nifD
Nitrogenase molybdenum-iron protein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.577
isfD
Sulfoacetaldehyde reductase; Catalyzes the formation of isethionate from 2- sulfoacetaldehyde in the deaminative pathway of taurine. The enzyme is specific for NADPH; NADH is not a substrate. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.563
hslO
Hsp33-like chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
 
   
 0.541
AKL35731.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0260 family.
  
     0.493
nifM
Peptidylprolyl isomerase; Required for the activation and stabilization of the iron- component (NifH) of nitrogenase. Probable PPIase; Belongs to the PpiC/parvulin rotamase family.
   
  
 0.476
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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