Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yfeXPeroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)    
Predicted Functional Partners:
efeO
Ferrous iron transporter; With EfeUB forms an iron transport system which is silent in E. coli K-12 due to a mutation in EfeU; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.725
yobA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.672
AKL35158.1
RpoE-regulated lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.658
yfeZ
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.622
katG
Peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
      
 0.605
efeU
Iron permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.561
bcp
Thiol peroxidase; Bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.552
katE
Hydroperoxidase; Serves to protect cells from the toxic effects of hydrogen peroxide.
     
 0.526
btuE
Similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.518
grxA_1
Glutaredoxin; Functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.495
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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