Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mgtEDihydroorotate dehydrogenase; Acts as a magnesium transporter. (478 aa)    
Predicted Functional Partners:
AKL35314.1
Multidrug transporter membrane component/ATP-binding component; Efflux pump for the antibacterial peptide microcin J25; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.716
citD_1
Citrate lyase subunit gamma; Covalent carrier of the coenzyme of citrate lyase.
      
 0.501
citD
Citrate lyase subunit gamma; Covalent carrier of the coenzyme of citrate lyase.
      
 0.501
citX
Acid phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.497
citS
Citrate:sodium symporter; Uptake of citrate across the boundary membrane with the concomitant uptake of a sodium ion (symport system). Belongs to the sodium:citrate (SCF) symporter family.
      
 0.474
AKL37011.1
PTS fructose transporter subunit IIA; Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein HPr; HPr transfers the phosphoryl group to subunit A; subunit IIA transfers a phosphoryl group to subunit IIB; subunit IIB transfers the phosphoryl group to the substrate; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.437
AKL35312.1
6-O-methylguanine DNA methyltransferase; Regulates genes involved in the repair of alkylated DNA; repairs DNA containing 6-O-methylguanine; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.430
AKL35313.1
Alpha-ketoglutarate-dependent dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.422
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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