STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fghAS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (278 aa)    
Predicted Functional Partners:
frmA
Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.999
AKL33635.1
Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.900
AKL33636.1
Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
  0.900
fdoH
Formate dehydrogenase; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
     
  0.900
fdoI
Formate dehydrogenase; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
frmR
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.741
rcnR
Transcriptional repressor rcnR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.646
yghU
S-transferase; YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.512
yfcE
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.503
AKL34803.1
Transcriptional regulator; Regulates the expression of formate dehydrogenase H and hydrogenase-3 structural genes; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.499
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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