STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKL35374.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)    
Predicted Functional Partners:
rsd
anti-RNA polymerase sigma 70 factor; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
  
     0.766
AKL34360.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.645
ycgB
SpoVR family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.634
bfd
Bacterioferritin-associated ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.625
yohD
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.607
yqcC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.584
ligB
NAD-dependent DNA ligase LigB; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
  
     0.539
AKL35008.1
DTW domain-containing protein YfiP; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.478
elaB_2
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.473
smrA_2
DNA endonuclease SmrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.456
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.