Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKL35385.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)    
Predicted Functional Partners:
AKL35021.1
Signal peptidase I; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
   
    0.783
yehU
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.740
yehT
Two-component response-regulatory protein YehT; Unknown function; when overproduced it confers drug-resistance; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.725
yaeQ
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.664
AKL34294.1
Metal-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.657
rimO
Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
  
    0.649
AKL35184.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.588
AKL36778.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.580
kstR2_2
DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.573
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.568
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.