Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bepDMultidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (417 aa)    
Predicted Functional Partners:
mdtC
Multidrug transporter; Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
 
 
 0.999
mdtB
Multidrug transporter; Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 
 
 0.999
baeS_2
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.969
mdtD_1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.946
spy
Periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.942
baeR
Response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.933
AKL35672.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.912
acrB_1
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.846
tolC
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.829
bepE_2
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.774
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: medium (46%) [HD]