Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL38827.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa)    
Predicted Functional Partners:
AKL35436.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.953
yycF
Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.819
arlR
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.816
phoP_1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.809
walR
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.809
AKL35286.1
Transcriptional activator of tricarboxylate transport system genes; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.805
phoB
Transcriptional regulator PhoB; Two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.802
baeR
Response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.800
AKL38268.1
Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.800
basR_3
Response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.793
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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