Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nifFFlavodoxin; Low-potential electron donor to a number of redox enzymes. NifF is the electron donor to nitrogenase; Belongs to the flavodoxin family. (176 aa)    
Predicted Functional Partners:
nifJ
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.889
nifZ
Protein NifZ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NifZ family.
 
   
 0.796
nifD
Nitrogenase molybdenum-iron protein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.734
nifH
Nitrogenase reductase; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
 
   
 0.719
nifM
Peptidylprolyl isomerase; Required for the activation and stabilization of the iron- component (NifH) of nitrogenase. Probable PPIase; Belongs to the PpiC/parvulin rotamase family.
  
  
 0.685
nifB
Nitrogen fixation protein NifB; Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.
 
   
 0.627
nifU_1
Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
      
 0.615
nifL
Nitrogen fixation protein; Required for the inhibition of NifA activity in response to oxygen and low level of fixed nitrogen.
 
   
 0.593
AKL35480.1
Iron-molybdenum cofactor biosynthesis protein NifQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.589
AKL36164.1
2,3-dihydro-2,3-dihydroxybenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.580
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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