Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nifMPeptidylprolyl isomerase; Required for the activation and stabilization of the iron- component (NifH) of nitrogenase. Probable PPIase; Belongs to the PpiC/parvulin rotamase family. (266 aa)    
Predicted Functional Partners:
nifZ
Protein NifZ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NifZ family.
 
   
 0.944
nifW
Nitrogen fixation protein NifW; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family.
     
 0.889
AKL35487.1
Homocitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
   
 0.880
AKL35488.1
Cysteine desulfurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
 
  
 0.798
nifH
Nitrogenase reductase; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
  
  
 0.785
nifD
Nitrogenase molybdenum-iron protein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.770
ppiC_1
Peptidylprolyl isomerase; Rotamase C; accelerates isomerization of the peptidyl prolyl bond; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.765
ppiC_2
Peptidylprolyl isomerase; Rotamase C; accelerates isomerization of the peptidyl prolyl bond; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.765
nifJ
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.760
AKL35489.1
Nitrogen fixation protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
 
  
 0.750
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.