Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
nifWNitrogen fixation protein NifW; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family. (86 aa)    
Predicted Functional Partners:
nifZ
Protein NifZ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NifZ family.
     
 0.890
nifM
Peptidylprolyl isomerase; Required for the activation and stabilization of the iron- component (NifH) of nitrogenase. Probable PPIase; Belongs to the PpiC/parvulin rotamase family.
     
 0.889
AKL35487.1
Homocitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.
       0.773
AKL35488.1
Cysteine desulfurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
       0.752
AKL35489.1
Nitrogen fixation protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
       0.680
nifF
Flavodoxin; Low-potential electron donor to a number of redox enzymes. NifF is the electron donor to nitrogenase; Belongs to the flavodoxin family.
      
 0.470
nifD
Nitrogenase molybdenum-iron protein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.463
nifU_1
Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
     
 0.451
AKL35490.1
Nitrogen fixation protein NifX; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.414
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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