Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
sbmCDNA gyrase inhibitor; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell. (157 aa)    
Predicted Functional Partners:
yeeA
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.760
bcsE
Required for cellulose biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.747
AKL36272.1
Heat-inducible protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.729
yjjQ
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.722
AKL37371.1
acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.717
ihfA
Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
   
  
 0.710
chiP
Chitoporin; Outer membrane porin involved in the transport of chitooligosaccharides; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.693
AKL36371.1
LpxA-like enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.667
AKL35291.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.645
sulA
SOS cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
  
    0.608
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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