STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (246 aa)    
Predicted Functional Partners:
cobU
Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
 
 
 0.988
btuR_2
cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
 
 0.973
AKL37417.1
cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
 
 0.973
AKL37491.1
Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family.
 
 
 0.966
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 
 0.949
cbiH
Catalyzes the formation of cobalt-precorrin-4 from cobalt-precorrin-3B; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.948
cobQ
Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.933
cbiL
Cobalt-precorrin-2 C(20)-methyltransferase; Catalyzes the formation of precorrin-3A from precorrin-2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.904
AKL35141.1
Ethanolamine utilization cobalamin adenosyltransferase; Catalyzes the conversion of cob(I)yrinic acid a,c-diamide to adenosylcob(III)yrinic acid a,c-diamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.900
cbiC
precorrin-8X methylmutase; Catalyzes the interconversion of cobalt-precorrin-8X and cobyrinic acid in the anaerobic biosynthesis of cobalamin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.885
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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