STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKL35563.1DNA cytosine methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)    
Predicted Functional Partners:
vsr
Very short patch repair endonuclease; DNA mismatch endonuclease; recognizes and repairs T:G mismatches; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.950
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.920
AKL35508.1
Adenosylhomocysteinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.906
mtnN
5'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/U [...]
    
  0.903
speD
S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
     
  0.900
AKL34963.1
Tail fiber protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.646
AKL34932.1
Excisionase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.630
AKL38296.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.630
AKL35562.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.615
yedR
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.497
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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