Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
treATrehalase; Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system; Belongs to the glycosyl hydrolase 37 family. (582 aa)    
Predicted Functional Partners:
otsB
Trehalose phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 0.976
AKL36523.1
Malto-oligosyltrehalose trehalohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.943
AKL35977.1
Glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.906
treC
Trehalose-6-phosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.906
treF
Trehalase; Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
  
  
 
0.905
aglB
6-phospho-alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
AKL35519.1
6-phospho-alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
galM
Galactose-1-epimerase; Converts alpha-aldose to the beta-anomer.
  
 
  0.564
srlA
PTS system glucitol/sorbitol-specific transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.560
glk
Glucokinase; Catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family.
    
 0.544
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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