Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
btuCVitamin B12 import system permease BtuC; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. (328 aa)    
Predicted Functional Partners:
btuD
Vitamin B12-transporter ATPase; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
 
 
 0.996
btuF
Vitamin B12-transporter protein BtuF; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
 
 
 0.988
fhuC_2-2
Iron-hydroxamate transporter ATP-binding subunit; Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.767
yusV_3
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.766
yusV_4-2
Iron-enterobactin transporter ATP-binding protein; With FepBDE is involved in the transport of ferric enterobactin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.766
yusV_4
Iron ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.764
hmuV
Hemin importer ATP-binding subunit; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
  
     0.754
AKL36196.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.720
AKL34785.1
Hemin ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.694
AKL35884.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.689
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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