Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL35935.1Acetoin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)    
Predicted Functional Partners:
budA
Alpha-acetolactate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-acetolactate decarboxylase family.
 
  
 0.988
AKL37565.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.917
AKL34570.1
Diacetyl reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
0.906
AKL35936.1
Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
 
 0.855
gldA_1
Oxidoreductase; Member of the iron-containing alcohol dehydrogenase family; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.613
benM_1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
     
 0.582
gldA
Glycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.569
nuoC
NADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
   0.564
gldA-2
Glycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.554
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.539
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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