STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKL35998.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (79 aa)    
Predicted Functional Partners:
nrdB
Ribonucleotide-diphosphate reductase subunit beta; B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.675
AKL35301.1
2Fe-2S ferredoxin; Plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.666
AKL35303.1
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
     0.654
AKL35999.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.630
yfbV
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.574
yihI
GTPase activator; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.547
AKL34283.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.533
syd
Secretion protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.
  
     0.528
AKL35997.1
Transcriptional repressor NemR; Represses nemA which is involved in degradation of N-ethylmaleimide; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.527
yifE
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.523
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.