STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uspEUniversal stress protein UspE; With UspC and UspD is involved in resistance to UV irradiation; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)    
Predicted Functional Partners:
fnr
Transcriptional regulator; Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism. When the terminal electron acceptor, O(2), is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration (By similarity).
 
  
 0.833
AKL36103.1
Universal stress protein UspG; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
   
  
 0.768
uspA_1
Universal stress global response regulator UspA; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
   
  
 0.757
yfbV
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.746
pspC
Transcriptional regulator; With PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.737
metJ
Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
     0.716
uspG
Universal stress protein UspG; Interacts with GroEL; is induced by starvation, heat shock and toxic agents; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.704
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
 
  
 0.681
uspF
Universal stress protein F; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.674
uspA_2
Universal stress protein UspC; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
   
  
 0.649
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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