Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL36059.13-carboxy-cis,cis-muconate cycloisomerase; Catalyzes the cycloisomerization of cis,cis-muconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)    
Predicted Functional Partners:
AKL36061.1
4-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
pcaH
Protocatechuate 3,4-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.990
pcaG
Protocatechuate 3,4-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.988
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.969
AKL33563.1
4-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.951
AKL36220.1
4-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.949
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.946
AKL36060.1
3-oxoadipate enol-lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.938
purK
Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
 
 0.920
AKL36550.1
Carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.919
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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