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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL38859.1D-mannonate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannitol dehydrogenase family. (487 aa)    
Predicted Functional Partners:
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
 
 0.960
uxaC
Glucuronate isomerase; Catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.957
rspA_1
Bifunctional D-altronate/D-mannonate dehydratase; Starvation-sensing protein; maybe involved in homoserine lactone degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.947
AKL36101.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.930
AKL34782.1
2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.911
por_3
D-mannonate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.903
mtlA_1
PTS system mannitol-specific transporter subunit IICBA; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIC forms the translocation channel and contains the specific substrate-binding site; subunit IIA is phosphorylated and transfers the phosphoryl group to the IIB subunit; subunit IIB transfers the phosphoryl group to the substrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.873
AKL38502.1
Transcription antiterminator BglG; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.674
AKL34289.1
Altronate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.601
fruB_3
Bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HPr which then transfers the phosphoryl group to the IIB component; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.530
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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