STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKL36162.1Pyoverdin chromophore biosynthetic protein pvcC; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)    
Predicted Functional Partners:
hpaC
4-hydroxyphenylacetate 3-monooxygenase; Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH. Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion (By similarity).
 
 
 0.951
hpcB
3,4-dihydroxyphenylacetate 2,3-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.912
hpaB
Pyoverdin chromophore biosynthetic protein pvcC; Utilizes FADH(2) supplied by HpaC or by another flavin reductase, to catalyze the hydroxylation of 4-hydroxyphenylacetic acid, leading to the production of 3,4-DHPA.
  
  
 
0.903
AKL36163.1
Phenazine-specific anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.703
AKL36164.1
2,3-dihydro-2,3-dihydroxybenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.577
AKL36165.1
2,3-dihydroxybenzoate-2,3-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.545
AKL36166.1
Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.545
mhpD_2
2-oxo-hepta-3-ene-1,7-dioate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.543
mhpD
2-keto-4-pentenoate hydratase; Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid. Belongs to the hydratase/decarboxylase family. MhpD subfamily.
 
   
 0.528
hpcD
5-carboxymethyl-2-hydroxymuconate delta-isomerase; Catalyzes the formation of 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid from 5-carboxymethyl-2-hydroxy-muconic acid; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.454
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.