Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL36164.12,3-dihydro-2,3-dihydroxybenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)    
Predicted Functional Partners:
entE
Enterobactin synthase subunit E; Bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
entF
Enterobactin synthase subunit F; With EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.996
AKL36168.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.992
AKL36163.1
Phenazine-specific anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.990
AKL37545.1
Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.988
AKL37553.1
Invasin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.987
AKL36167.1
Thioester reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.985
AKL36165.1
2,3-dihydroxybenzoate-2,3-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.980
fepB
Iron-enterobactin ABC transporter substrate-binding protein; With FepCDG is involved in the transport of ferric enterobactin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.962
AKL35548.1
Salmochelin siderophore protein IroE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.960
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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