Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (262 aa)    
Predicted Functional Partners:
putA
Transcriptional regulator; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
   
 0.966
proC_2
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
  
 
0.920
pip
Proline iminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.902
AKL36187.1
Glyoxalase-like domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.812
AKL34620.1
Racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/glutamate racemases family.
     
  0.800
AKL36185.1
Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.758
AKL36186.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.756
AKL36184.1
Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.754
AKL36183.1
Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.745
proB
Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.731
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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