Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKL36224.12-dehydropantoate 2-reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)    
Predicted Functional Partners:
AKL37817.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
  
  0.930
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.921
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.921
AKL35313.1
Alpha-ketoglutarate-dependent dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.597
AKL33773.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.546
AKL35926.1
Type VI secretion protein VasK; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.541
AKL36223.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.525
AKL35445.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.486
AKL33838.1
Polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.444
rcnB_2
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.442
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (20%) [HD]