Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKL38869.1Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)    
Predicted Functional Partners:
yaeQ
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.906
AKL35021.1
Signal peptidase I; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
   
  
 0.900
cspE
Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.834
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
  
 0.805
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.753
AKL36778.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.735
raiA
Translation inhibitor protein RaiA; Associated with 30S ribosomal subunit; interferes with translation elongation; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.732
kstR2_2
DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.692
rne
Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
   
    0.683
AKL34623.1
Fimbrial chaperone protein; Member of the periplasmic pilus chaperone family of proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.681
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.