Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL36272.1Heat-inducible protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)    
Predicted Functional Partners:
chiP
Chitoporin; Outer membrane porin involved in the transport of chitooligosaccharides; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.740
bcsE
Required for cellulose biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.730
sbmC
DNA gyrase inhibitor; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
  
     0.729
yjjQ
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.690
AKL37371.1
acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.685
lolD-2
Macrolide transporter; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
   
   0.682
AKL34766.1
Macrolide transporter; With MacA is involved in the export of macrolide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
   
   0.682
macB_1
Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
   
   0.682
mtlR
Mannitol repressor protein; Acts as a repressor of the mtlAD operon; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.669
AKL36371.1
LpxA-like enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.656
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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