Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
paaKphenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (438 aa)    
Predicted Functional Partners:
paaA
ATPase AAA; With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.996
paaB
phenylacetate-CoA oxygenase; With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.996
paaI
acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.996
AKL36329.1
Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.995
AKL36328.1
Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
AKL36330.1
Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.990
AKL36282.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
  
 0.921
AKL36542.1
Amidase; Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the amidase family.
    
  0.904
AKL37585.1
Amidase; Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the amidase family.
    
  0.903
AKL38366.1
Acetamidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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