STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adrA_2Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)    
Predicted Functional Partners:
AKL34728.1
Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.954
AKL34195.1
Aerobic respiration control sensor protein ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.896
AKL36516.1
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.854
AKL37764.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.839
AKL35710.1
c-di-GMP phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.806
AKL38743.1
Biofilm formation regulator HmsP; HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.804
AKL38695.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.803
ycgG_1
Involved in resistance to the phages N4 and lambda; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.799
AKL36119.1
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.745
rcsC
Histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
 0.706
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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