Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL36367.1Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the type-B carboxylesterase/lipase family. (502 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  0.705
AKL36366.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.661
AKL33640.1
Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.601
ywaD
Alkaline phosphatase; Catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.516
mdoD
Glucan biosynthesis protein D; Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs). Belongs to the OpgD/OpgG family.
     
 0.491
rpsA
30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
   
 
  0.483
ycaC_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.480
rpsE
30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
     
  0.453
sbcC
Exonuclease SbcC; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SMC family. SbcC subfamily.
    
   0.453
AKL34802.1
Pectin acetylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.422
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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