Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smvAMethyl viologen resistance protein SmvA; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)    
Predicted Functional Partners:
AKL36438.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.812
AKL37081.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.651
bm3R1_1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.567
mdtK
Multidrug transporter; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
  
  
 0.550
betI
Transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes.
      
 0.496
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
 0.495
tkt-2
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
 0.495
fieF
Ferrous iron transporter; Cation-efflux transporter that may have a role in detoxification.
      
 0.491
mdtL
Multidrug transporter; Confers resistance to chloramphenicol; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.428
AKL36163.1
Phenazine-specific anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.406
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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