Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
pspDPhage-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa)    
Predicted Functional Partners:
pspB
Phage shock protein; DNA-binding transcriptional regulator; acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.991
pspC
Transcriptional regulator; With PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.984
pspA
Phage shock protein; Involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.967
pspE
Thiosulfate:cyanide sulfurtransferase; Rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.804
pspF
Phage shock protein; Transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.756
AKL38889.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.744
AKL36703.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.743
pspG
Phage shock protein; Coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.619
hflB
ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
      
 0.563
trxA
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
      
 0.470
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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