Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sppA_1Protease 4; SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. (617 aa)    
Predicted Functional Partners:
AKL36801.1
Nicotinamidase/pyrazinamidase; Catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.655
clpP
Hypothetical protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
      
 0.623
ydjA
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.598
ansA
Cytoplasmic asparaginase I; Converts asparagine to aspartate and ammonia; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.588
znuA
Zinc ABC transporter substrate-binding protein; Involved in transport of zinc(II) with ZnuA and C; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.504
AKL38752.1
Nicotinate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAPRTase family.
      
 0.461
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
   
 0.440
prs
Ribose-phosphate pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.427
AKL36810.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.424
AKL38460.1
HNH endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.424
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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