Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fecDIron-dicitrate transporter subunit FecD; Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter; Derived by automated computational an [...] (317 aa)    
Predicted Functional Partners:
yusV_4
Iron ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.994
fecB
Iron-dicitrate transporter substrate-binding subunit; Part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+); Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.980
fecC
Iron-dicitrate transporter permease subunit; Part of the FecBCDE citrate-dependent iron (III) transport system; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 
0.961
hmuV
Hemin importer ATP-binding subunit; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
 
 
 0.899
yusV_3
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.886
yusV_4-2
Iron-enterobactin transporter ATP-binding protein; With FepBDE is involved in the transport of ferric enterobactin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.885
fhuC_2-2
Iron-hydroxamate transporter ATP-binding subunit; Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.884
AKL36196.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.853
AKL35882.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.798
AKL34785.1
Hemin ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.786
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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