Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
putPProline:sodium symporter PutP; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (502 aa)    
Predicted Functional Partners:
putA
Transcriptional regulator; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
  
 0.966
AKL38259.1
Sodium:alanine symporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.706
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
   
 0.638
AKL34195.1
Aerobic respiration control sensor protein ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.635
betI
Transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes.
      
 0.578
AKL34397.1
Anion transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.573
betP
Proton-motive-force-driven choline transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BCCT transporter (TC 2.A.15) family.
 
  
 0.562
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
      
 0.559
AKL36985.1
Choline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.549
AKL35941.1
Sodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.541
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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