STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfsANADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flavin oxidoreductase frp family. (240 aa)    
Predicted Functional Partners:
AKL37606.1
Dihydropteridine reductase; Catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.930
AKL37280.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.916
AKL35996.1
N-ethylmaleimide reductase; FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.907
lysX
Ribosomal protein S6 modification protein; Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RimK family.
  
  
 0.713
birA
biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.656
AKL37226.1
Ribosomal protein S12 methylthiotransferase accessory factor YcaO; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.620
slmA
Division inhibitor protein; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
      
 0.602
AKL35997.1
Transcriptional repressor NemR; Represses nemA which is involved in degradation of N-ethylmaleimide; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.602
AKL36916.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.602
bm3R1_2
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.602
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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