Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ybiSL,D-transpeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)    
Predicted Functional Partners:
AKL34220.1
D-alanyl-D-alanine carboxypeptidase; Penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.654
lpp
Major outer membrane lipoprotein; interacts with peptidoglycan to maintain the integrity of the cell envelope; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.654
AKL37207.1
Murein L,D-transpeptidase; Catalyzes the formation of a meso-diaminopimelyl- meso-diaminopimelyl crosslink; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.621
ftsI
Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
  
  
 0.582
AKL37877.1
This protein has no known enzymatic function; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.543
AKL37289.1
Peptidase M15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.
  
 
 0.540
AKL37497.1
D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.
  
 
 0.540
dacD
D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.
    
 0.539
mrcA
Penicillin-binding protein 1A; Bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.537
mrdA
Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
     
 0.523
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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