Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ybhTMembrane protein; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. (49 aa)    
Predicted Functional Partners:
tolC
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.697
AKL33425.1
Macrolide transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
    
 
 0.667
macA_4
Macrolide transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
    
 
 0.667
AKL38932.1
Transcriptional regulator; Represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.664
AKL37594.1
RND transporter MFP subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
    
 
 0.639
AKL35987.1
Transporter; Uncharacterized member of the major facilitator superfamily (MFS); Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.625
emrD
Multidrug efflux protein involved in adaptation to low energy shock; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.604
bcr_3
Bicyclomycin/multidrug efflux system; Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.602
ybjP
Lipoprotein; Induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.595
bcr_1
Major facilitator transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.588
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.