Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKL37395.1Zinc transporter ZitB; Involved in zinc efflux across the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)    
Predicted Functional Partners:
copA
Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.702
AKL38767.1
Zinc transporter ZupT; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.574
AKL37394.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.565
zntA
Zinc ABC transporter ATPase; P-type ATPase involved in the export of lead, cadmium, zinc and mercury; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.551
uraH
Hydroxyisourate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
  
    0.537
AKL36288.1
FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.537
mntH
Manganese transport protein MntH; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
  
 
 0.528
zntR
Zinc-responsive transcriptional regulator; Mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.513
zntB
Zinc transporter; Mediates efflux of zinc ions; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
 
   
 0.444
metJ
Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
      
 0.439
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (10%) [HD]