STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (347 aa)    
Predicted Functional Partners:
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
 0.998
AKL38145.1
Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family.
 
 
 0.996
nadX
Aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
    
 0.928
AKL37396.1
Involved in nicotinamide riboside transport; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.920
AKL34078.1
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.731
AKL33528.1
Involved in nicotinamide riboside transport; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.698
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.661
cysE
Catalyzes the O-acetylation of serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transferase hexapeptide repeat family.
  
    0.646
AKL38004.1
Colanic acid biosynthesis acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transferase hexapeptide repeat family.
  
    0.646
queE
Pyrroloquinoline quinone biosynthesis protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
   
 0.571
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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