Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cadALysine decarboxylase LdcC; Constitutive; catalyzes the formation of cadaverine from lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. (715 aa)    
Predicted Functional Partners:
patA
Putrescine--2-oxoglutarate aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
  
 
 0.918
ldcC
Lysine decarboxylase LdcC; Constitutive; catalyzes the formation of cadaverine from lysine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.901
AKL34620.1
Racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/glutamate racemases family.
     
  0.900
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
 0.833
cadB
Antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.832
AKL33667.1
ATPase; Interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.728
AKL37659.1
Peptide permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.623
AKL35213.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.449
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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