Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL37710.1Hydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family. (258 aa)    
Predicted Functional Partners:
gcl
Glyoxylate carboligase; Catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
 
 
 0.993
AKL37709.1
Tartronate semialdehyde reductase; NADH-dependent; catalyzed the reversible formation of glycerate from tartronate semialdehyde; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.989
garR
Tartronate semialdehyde reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
 
 0.968
ghrA
Bifunctional glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
  
 
  0.937
AKL38792.1
2-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.935
ghrB
Bifunctional glyoxylate/hydroxypyruvate reductase B; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
  
 
 0.921
garL
alpha-dehydro-beta-deoxy-D-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
     
  0.800
AKL37712.1
Transcriptional regulator; Regulates operons involved in the utilization of allantoin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.530
AKL38130.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.524
AKL37707.1
Allantoin permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.510
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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