Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
copACopper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (833 aa)    
Predicted Functional Partners:
sodC
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
  
 0.988
zntA
Zinc ABC transporter ATPase; P-type ATPase involved in the export of lead, cadmium, zinc and mercury; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.889
cueR
Transcriptional regulator; Activator of copper-responsive regulon genes; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.802
dps
DNA starvation/stationary phase protection protein Dps; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction; Belongs to the Dps family.
  
  
 0.761
ppiA
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
 
   0.749
AKL37727.1
Conjugal transfer protein TraB; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.734
ppiB
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
 
   0.731
AKL38123.1
Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.709
AKL37395.1
Zinc transporter ZitB; Involved in zinc efflux across the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.702
ftsP
Cell division protein FtsI; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress; Belongs to the FtsP family.
 
 
 0.701
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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