STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ushA5'-nucleotidase; Catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. (550 aa)    
Predicted Functional Partners:
udk
Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.948
add
Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
  
 0.933
cpdB
Periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family.
 
 
0.932
tdk
Thymidine kinase; Catalyzes the formation of thymidine 5'-phosphate from thymidine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.929
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
 
  
 0.928
yjjG
dUMP phosphatase; Manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.926
AKL38752.1
Nicotinate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAPRTase family.
 
  
 0.923
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.920
AKL35180.1
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.920
deoD
Purine nucleoside phosphorylase; Catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.920
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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