Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
acrA_1Multidrug transporter; With AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (397 aa)    
Predicted Functional Partners:
AKL37746.1
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
tolC
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.989
AKL33770.1
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.988
AKL36512.1
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.988
AKL37593.1
Multidrug RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.983
AKL38437.1
Acriflavine resistance protein B; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.971
AKL37061.1
Acriflavine resistance protein B; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.967
AKL37594.1
RND transporter MFP subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 
0.923
mexA
Acriflavine resistance protein E; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 
0.904
AKL34141.1
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.896
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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