Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lacITranscriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)    
Predicted Functional Partners:
AKL38929.1
Cytochrome C peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.770
AKL38409.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.769
AKL35401.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.745
AKL37672.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.569
gltB
Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.540
rpmE2
50S ribosomal protein L31; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.536
tuf-2
Elongation factor Tu; EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.521
rpmJ
50S ribosomal protein L36; Smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.512
matP
Ter macrodomain organizer matS-binding protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
    
 
 0.503
lamB_4
Maltoporin; Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family.
 
     0.501
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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