| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKL34220.1 | ampG | AB185_10070 | AB185_29540 | D-alanyl-D-alanine carboxypeptidase; Penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; Derived by automated computational analysis using gene prediction method: Protein Homology. | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.553 |
| AKL34220.1 | ftsI | AB185_10070 | AB185_18160 | D-alanyl-D-alanine carboxypeptidase; Penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.588 |
| AKL34220.1 | nagZ | AB185_10070 | AB185_24765 | D-alanyl-D-alanine carboxypeptidase; Penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; Derived by automated computational analysis using gene prediction method: Protein Homology. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.407 |
| AKL37545.1 | ampG | AB185_28225 | AB185_29540 | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.654 |
| AKL37545.1 | entE | AB185_28225 | AB185_28220 | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Enterobactin synthase subunit E; Bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.990 |
| AKL37545.1 | menF | AB185_28225 | AB185_15830 | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.927 |
| AKL37545.1 | pchB | AB185_28225 | AB185_25285 | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.972 |
| AKL37795.1 | ampG | AB185_29535 | AB185_29540 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.673 |
| ampG | AKL34220.1 | AB185_29540 | AB185_10070 | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-alanyl-D-alanine carboxypeptidase; Penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.553 |
| ampG | AKL37545.1 | AB185_29540 | AB185_28225 | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.654 |
| ampG | AKL37795.1 | AB185_29540 | AB185_29535 | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.673 |
| ampG | emrD | AB185_29540 | AB185_07450 | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multidrug efflux protein involved in adaptation to low energy shock; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.588 |
| ampG | entE | AB185_29540 | AB185_28220 | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Enterobactin synthase subunit E; Bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.709 |
| ampG | ftsI | AB185_29540 | AB185_18160 | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.549 |
| ampG | macB_1 | AB185_29540 | AB185_26620 | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.635 |
| ampG | menF | AB185_29540 | AB185_15830 | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.654 |
| ampG | nagZ | AB185_29540 | AB185_24765 | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.557 |
| ampG | pchB | AB185_29540 | AB185_25285 | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.651 |
| emrD | ampG | AB185_07450 | AB185_29540 | Multidrug efflux protein involved in adaptation to low energy shock; Derived by automated computational analysis using gene prediction method: Protein Homology. | Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.588 |
| emrD | macB_1 | AB185_07450 | AB185_26620 | Multidrug efflux protein involved in adaptation to low energy shock; Derived by automated computational analysis using gene prediction method: Protein Homology. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.635 |