STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolS_1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)    
Predicted Functional Partners:
dkgA
2,5-diketo-D-gluconic acid reductase; Methylglyoxal reductase/beta-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.657
dxs_5
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.651
AKL36073.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.650
AKL35436.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.575
phoP_1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.575
walR
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.575
ispA
Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family.
     
 0.560
xseB
Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
       0.551
arlR
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.543
dkgB
Catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.518
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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