Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gntR_3-3Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)    
Predicted Functional Partners:
galR_2
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.773
rafR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.770
cytR_5
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.747
AKL38929.1
Cytochrome C peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.747
AKL37672.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.613
AKL37868.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.587
gltB
Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.540
gno_2
Gluconate 5-dehydrogenase; Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.468
AKL37011.1
PTS fructose transporter subunit IIA; Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein HPr; HPr transfers the phosphoryl group to subunit A; subunit IIA transfers a phosphoryl group to subunit IIB; subunit IIB transfers the phosphoryl group to the substrate; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.451
iraP
Anti-adapter protein IraP; Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
       0.432
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.